最新药理学英文习题(教研室版)

　　精品文档

　　I .Choice Questions

　　Type A

　　1 .The half-life of a drug is 2 hours, how much is the K? -1

　　A. 0.1 (h -1) B. 0.2 (h) C. 0.3 (h-1) D. 0.35 (h ) E. 2 (h)

　　2. Which of the following statements about first-order kinetics elimination is true? A. The elimination rate is fast B. The elimination rate is slow

　　C. There is no relationship between the amount of drug in the body

　　and elimination rate

　　D. The elimination of drug is in direct proportion to the blood concentration of the drug E. The elimination of drug is in inverse ratio to the amount of drug

　　in the body

　　3. As far as some drug is concerned, which of the following statements concerning the drug's combination with plasma

　　protein is true?

　　A. The higher the binding rate, the stronger the curative effect B. The lower the binding rate, the stronger the curative effect C. The higher the binding rate, the faster the excretion

　　D. There is not relationship between binding rate and curative effect E. All of the above are incorrect

　　4. Which of the following administrations can immediately reach the plateau concentration? A. Decreasing dose, increasing times of administration B. Decreasing administering interval C. Increasing administering interval D. Administration of loading dose E. Frequent administration by iv

　　5 .In general, the weak acid drugs in basic solution are A. weakly ionized, pass across the biomembrane easily B. strongly ionized, pass across the biomembrane easily C. strongly ionized, pass across the biomembrane hardly D. weakly ionized, pass across the biomembrane hardly E. all of above are incorrect

　　6. If the stomach juice pH is1. 4 and plasma pH is 7.4, how much is the drug concentration ratio of plasma to stomach juice for a weak acidic drug with pKa 5.4 when the distribution reach to equilibrium ？ A. 50 B. 100

　　C. 1000 精品文档 精品文档 D. 10000 E. 0.1

　　-1 -1

　　-1 -1-1 -1

　　7. All of the following statements are applicable to the sublingual route of administration EXCEPT A. plasma concentration decreased by first pass elimination B. lipid soluble drugs will be absorbed rapidly C. Irritant drugs should not be given by this route D. blood flow through the mucosa is high

　　E. taste of drugs limits the usefulness of this route 8. Which of the following can be advisable to treat hemorrhage of digestive tract? A. Norepinephrine oral administration B. Norepinephrine iv administration C. Norepinephrine im administration

　　D. Norepinephrine subcutaneous injection E. Adrenaline oral administration 9. Phentolamine can most likely be used to treat A. peripheral arterial spasm B. angina pectoris C. arrhythmia D. hypertension E. peptic ulcer

　　10. Which of the following drugs can be used to treat intoxication of succinylcholine?

　　A. Neostigmine B. Atropine C. Adrenaline

　　D. Pyraloxime methiodide E. Nikethamide

　　11. Which of the following drugs can be administered sublingually or inhaled in treating bronchi asthma?

　　A. Adrenaline B. Isoprenaline C. Ephedrine D. Phenylephrine E. Aminophylline 12. After injection of propranolol, the influence of phentolamine on blood pressure is

　　A. first up, then down B. up only C. down only

　　D. first down, then up E. the same as before

　　13. Which of the following drugs could pass through the blood-brain barrier and cause insomnia 精品文档

　　精品文档 A. Adrenaline B. Dopamine C. Ephedrine D. Isoprenaline E. Norepinephrine

　　14. Which of the following is not the contraindication of 3 -receptor blockers?

　　A. chronic heart failure B. atrioventricular block C. bronchial asthma D. high blood pressure E. sinus bradycardia

　　15. Which of the following drugs would be used to treat myasthenia gravis? A. Atropine B. Neostigmine C. Acetylcholine D. Scopolamine E. Carbachol

　　16. Which of the following sympathomimetic agents will most likely

　　lead to arrhythmia and ventricular fibrillation? A. Ephedrine B. Adrenaline C. Metaraminol D. Dopamine E. Norepinephrine

　　17. In which of the following conditions atropine can most likely be contraindicated

　　A. Glaucoma B. Intestinal spasm C. Infective shock D. Iridocyclitis E. All of above

　　18. Which of the following drugs can be used to treat heart cardiac failure caused by myocardial infarction?

　　A. Atropine B. Isoprenaline C. Dobutamine D. Norepinephrine E. Ephedrine

　　19. Which of the following drugs is applicable to treat allergic shock?

　　A. Isoproterenol B. Adrenaline