兰州大学研究生导师名单
陈文江,教授,兰州大学哲学社会学院社会学系系主任,民族社会学博士生导师,社会学专业硕士研究生导师,长期从事社会学理论和方法教学和研究。主要研究方向为西部社会学、伦理学、民族社会学、道德社会学、文化社会学、社会研究方法,社会问题研究、社会性别研究、文化社会学研究。
学习经历
1996 香港中文大学生物系 博士
1985 兰州大学生物系 硕士
1982 兰州大学生物系 学士
工作经历
主要工作简历:
02/1986-10/1988 兰州大学生物系 助教
10/1988-01/1993 兰州大学生物系 讲师
02/1989-06/1989 中科院上海植生所 合作科研
02/1997-11/1997 香港中文大学生物化学系 访问学者
11/1997-08/2000 兰州大学生物学流动站 工作
05/1999-12/2002 兰州大学生命科学学院 副教授
07/2004–今 兰州大学生命科学学院 教授
11/2003–今 兰州大学生命科学学院 博士生导师
10/2000-03/2001 香港中文大学生物系 合作科研
07/2003-01/2004 香港科技大学生物系 合作科研
10/2004–今 兰州大学生命科学学院 植物及植物生理研究所所长
02/2007-11/2007 香港科技大学生物系 合作科研
教学及指导研究生情况
本科生课程:植物生理学;植物生理学实验
研究生课程:高级植物生理学;植物呼吸代谢
发表论文及专著
主要发表文章:
Ping Li, Chengzhou Zhao, Yongqiang Zhang, Xiaomin Wang, Jianfeng Wang, Feng Wang, Yurong Bi*, Silicon enhances the tolerance of Poa annua to cadmium by inhibiting its absorption and oxidative stress, Biol Plantarum 2017, 61 (4): 741-750.
Feng Wang, Xiaomin Wang, Chengzhou Zhao, Jianfeng Wang, Ping Li, Yanqin Dou, Yurong Bi*, Alternative pathway is involved in the tolerance of highland barley to the low-nitrogen stress by maintaining the cellular redox homeostasis, Plant Cell Report, 2016, 35: 317-328.
Chengzhou Zhao, Xiaomin Wang, Xiaoyu Wang, Kunlun Wu, Ping Li, Ning Chang, Jianfeng Wang, Feng Wang, Jiaolong Li, Yurong Bi*, Glucose-6-phosphate dehydrogenase and alternative oxidase are involved in the cross tolerance of highland barley to salt stress and UV-B radiation, Jounal of Plant Physiology, 2015, 181: 83-95.
Jianfeng Wang, Yongqiang Zhang, Ying Li, Xiaomin Wang, Wenbin Nan, Yanfeng Hu, Hong Zhang, Chengzhou Zhao, Feng Wang, Ping Li, Hongyong Shi, Yurong Bi*, Endophytic microbes Bacillus sp. LZR216-regulated root development is dependent on polar auxin transport in Arabidopsis seedlings, Plant Cell Report, 2015, 34(6): 1075-1087.
Ping Li, Chengzhou Zhao, Yongqiang Zhang, Xiaomin Wang, Xiaoyu Wang, Jianfeng Wang, Feng Wang, Yurong Bi*, Calcium alleviates cadmium-induced inhibition on root growth by maintaining auxin homeostasis in Arabidopsis seedlings, Protoplasma, 2015, 253(1): 185-200.
Xiaolei Liang, Huahua Wang, Yanfeng Hu, Lina Mao, Lili Sun, Tian Dong, Wenbin Nan, Yurong Bi*, Silicon does not mitigate cell death in cultured tobacco BY-2 cells subjected to salinity without ethylene emission, Plant Cell Report, 2015, 34: 331-343.
Wenbin Nan, Xiaomin Wang, Lei Yang, Yanfeng Hu, Yantao Wei, Xiaolei Liang, Lina Mao, Yurong Bi*i, Cyclic GMP is involved in auxin signalling during Arabidopsis root growth and development, Journal of Experimental Botany, 2014, 65:1571-1583.
Yanfeng Hu, Jiaolong Li, Lijing Yang, Wenbin Nan, Xiaoping Cao, Yurong Bi*, Inhibition of root growth by narciclasine is caused by DNA damage-induced cell cycle arrest in lettuce seedlings, Protoplasma, 2014, 251:1113–1124.
Xiaomin Wang, chen Hou, Jie Liu, Wenliang He, Huiling Gong, chengyuan Shi, Yurong Bi*, Hydrogen peroxide plays a role in the regulation of rice (Oryza sativa L.) tolerance to salt stress, Acta Physiologiae Plantarum, 2013, 35(3): 891-900.
Jie Liu, Xiaomin Wang, Yanfeng Hu, Wei Hu, Yurong Bi*, Glucose-6-Phosphate dehydrogenase plays a pivotal role in tolerance to drought stress in soybean roots, Plant Cell Report, 2013, 32: 415-429.
Lei Zhang, Jie Liu, Xiaomin Wang, Yurong Bi*i, Glucose-6-phosphate dehydrogenase cooperated act as a regulator of cell redox balance in rice suspension cells under salt stress, Plant Growth Regulation, 2013, 69: 139-148.
Yinggao Liu, Qi Wan, Ruru Wu, Xiaomin Wang, Yurong Bi*, Role of hydrogen peroxide in regulating glucose-6-phosphate dehydrogenase expression and activity under salt stress, Biol Plantarum, 2012, 56 (2): 313-320.
Huiling Gong, Guishen Chen, Fengjuan Li, Xiaomin Wang, Yanfeng Hu, Yurong Bi*, (2012) Involvement of G6PDH in regulation of heat stress tolerance in the calli from Przewalskia tangutica and tobacco, Biol Plantarum, 2012, 56(3): 422-430.
Yanfeng Hu, Lijing Yang, Xiaofan Na, Xiaolei Liang, Xiaomin Wang, Yurong Bi*, Narciclasine inhibits responses of Arabidopsis roots to auxin, Planta, 2012, 236: 597-612.
Xiaolei Liang, Huahua Wang, Lina Mao, Yanfeng Hu, Tian Dong, Yongqiang Zhang, Xiaomin Wang, Yurong Bi*, Involvement of COP1 in ethylene- and light-regulated hypocotyl elongation, Planta, 2012, 236: 1791-1802.
Hongxia Lu, Qi Wan, Huahua Wang, Xiaofan Na, Xiaomin Wang Yurong Bi**, Oxidative stress and mitochondrial dysfunctions are early events in narciclasine-induced programmed cell death in tobacco Bright Yellow-2 cells, Physiologia Plantarum 2012, 144: 48–58.
Jisheng Li, Xiaomin Wang, Yanli Zhang, Honglei Jia, Yurong Bi*, cGMP regulates hydrogen peroxide accumulation in calcium-dependent salt resistance pathway in Arabidopsis thaliana roots, Planta, 2011, 234: 709-722.
Zeyong Zhang, Huahua Wang, Xiaomin Wang, Yurong Bi*, Nitric oxide enhances aluminum tolerance by affecting cell wall polysaccharides in rice roots, Plant Cell Report, 2011, 30: 1701-1711.
Xiaofan Na, Yanfeng Hu, Kun Yue, Hongxia Lu, Pengfei Jia, Huahua Wang, Xiaomin Wang, Yurong Bi*, Narciclasine modulates polar auxin transport in Arabidopsis roots, Journal of Plant Physiology, 2011, 168(11): 1149-1156.
Xiaofan Na, Yanfeng Hu, Kun yue, Hongxia Lu, Pengfei Jia, Huahua Wang, Xiaomin Wang, Yurong Bi*, Narciclasine affects the coordination between cell division and differentiation in Arabidopsis root tip, BMC Plant Biology, 2011, 11: 184.
Yongqiang Zhang, Sheng Zheng, Zhongjuan Liu, Liguang Wang, Yurong Bi*, HY5 and HYH are both necessary regulators for low temperature-induced anthocyanin accumulation in Arabidopsis seedlings, Journal of Plant Physiology 2011, 168:367-374.
Yongqiang Zhang, Zhongjuan Liu, Rongzhi Liu, Liguang Wang, Yurong Bi*, Gibberellins negatively regulate light-induced nitrate reductase activity in Arabidopsis seedlings, Journal of Plant Physiology 2011, 168: 2161-2168.
Zhongjuan Liu, Yongqiang Zhang, Rongzhi Liu, Hualing Hao, Zhi Wang, Yurong Bi*, Phytochrome interacting factors (pifs) are necessary regulators for sucrose-induced hypocotyl elongation in Arabidopsis. Journal of Plant Physiology, Journal of Plant Physiology 2011, 168:1771-1779.
Huahua Wang, Junjun Huang, Xiaolei Liang, Yurong Bi*, Involvement of hydrogen peroxide, calcium and ethylene in the induction of the alternative pathway in chilling-stressed Arabidopsis callus, Planta 2011, 235:53-67.
Xiao fan Na, Yanfeng Hu, Kun Yue, Hongxia Lu, Pengfei Jia, Huahua Wang, Xiaomin Wang, Yurong Bi*, Narciclasine affects the coordination between cell division and differentiation in Arabidopsis root tip, BMC Plant Biol 2011, 11:184.
Xiaomin Wang, Jisheng Li, Jie liu, Wenliang He, Yurong Bi*, Nitric oxide increases mitochondrial respiration in the cGMP-dependent manner in the callus from Arabidopsis, Nitric Oxide, 2010, 23: 242-250.
Lijun Ling, Yanzhuo Yang, Yurong Bi*, Expression and characterization of two domains of Pinellia ternate agglutinin (PTA), a plant agglutinin from Pinellia ternate with antifungal activity, World J Microbiol Biotechnol 2010, 26:545–554
Wang HH, Liang XL, Huang JJ, Zhang DK, Lu HX, Liu ZJ, Yurong Bi*, Involvement of ethylene and hydrogen peroxide in induction of alternative respiratory pathway in salt-treated Arabidopsis calluses, Plant Cell Physiol 2010, 51: 1754-1765
Yongqiang Zhang, Zhongjuan Liu, Liguang Wang, Sheng Zheng, Jiping Xie, Yurong Bi*, Sucrose-induced hypocotyl elongation of Arabidopsis seedlings in darkness depends on the presence of gibberellins. Journal of plant physiology 2010, 167(14):1130-1136
Huahua Wang, Xiaolei Liang, Qi Wan, Xiaomin Wang, Yurong Bi*, Ethylene and nitric oxide are involved in maintaining ion homeostasis in Arabidopsis callus under salt stress, Planta 2009, 230: 293-307
Xiaomin Wang, Yuanyuan Ma, Chenghong Huang, Qi Wan, Ning Li, Yurong Bi*, Glucose-6-phosphate dehydrogenase plays a central role in modulating reduced glutathione levels in reed callus under salt stress, Planta, 2008, 227:611-623.
Yingguao Liu, Ruru Wu, Qi Wan, Yurong Bi*, Glucose-6-phosphate dehydrogenase plays a pivotal role in nitric oxide-involved defense against oxidative stress under salt stress in red kidney bean roots, Plant Cell Physiollogy 2007,48:511-522
Mingguang Zhao, Yinggao Liu, Lixin Zhang, Lin Zhen, Yurong Bi*, Effects of enhanced UV-B radiation on the activity and expression of alternative oxidase in red kidney bean leaves, Journal of Integrative Plant Biol 2007, 49 (9): 1320–1326
研究方向
植物呼吸代谢, 植物抗性生理,植物化学及生物活性物质的生理生化活性的研究。
项目成果
主持项目:
国家自然科学基金面上项目,“青稞AOX与G6PDH功能及其抗逆机理研究”,2017.01.01-2020.12.31,62万
省、市、自治区科技项目“呼吸代谢在大豆抗旱适应性中的调节机理与信号转导研究”,2017.01.01-2020.12.31,10万
兰州市科技计划项目,“促进植物生长内生菌(PGPE)生物菌肥的研制及其对青稞生长和品质的影响”,2016.01.01-2017.12.31,10万
甘肃省科技计划项目,“冬小麦抗旱的生理与分子调控”,2013.11.01-2016.12.31,8万
国家自然科学基金面上项目,“呼吸代谢在植物应答和抵抗盐胁迫中的作用机制研究”,2012.01.01-2015.12.31,55万
甘肃省科技计划项目,“青稞对环境胁迫的生理响应及信号转导与分子机理研究”,2012.01.01-2015.12.31,3万
甘肃省科技计划项目,“冬小麦抗旱评价体系建立及抗旱分子机理研究”,2012.09.01-2016.09.30,9万
国家自然科学基金面上项目,“水仙生长抑制物Narciclasine化感作用的生理与分子生物学研究”,2006.01.01-2009.12.31,28万
教育部科技项目,“低温诱导花青素积累依赖于光的分子机理研究”,2011.01.01-2013.12.31,6万元
教育部科技项目,“G6PDH与NO在植物盐胁迫响应与信号传导中的协同作用”,2006.01.01-2008.12.31,6万元
荣誉、获奖
1. 《植物愈伤组织呼吸代谢研究》,获1987年甘肃省科技 进步三等奖;
2. 《植物发育的物质代谢与有关酶的调节研究》,分别获 1990年甘肃省教委科技进步一等奖和甘肃省科委科技进步二等奖(6/6);
3. 《植物呼吸代谢多条途经运行的调节及其生理意义》获 1997年教育部科技步二等奖(3/5);
4. 《植物主要膜系统电子传递生理功能与活性调节》,获 2004年教育部科技步二等奖(11/11);
5. 参加《植物生理学学习指导与题解》一书编写,华中科技大学出版社,2003,2007年再版;
6. 2009年被评为兰州大学“巾帼标兵”。
学习经历
1981-1985 学士, 兰州大学生物系植物生理专业
1985-1988 硕士, 兰州大学生物系植物生理专业
1991-1994 博士, 兰州大学生物系植物生理专业
1994-1996 博士后, 中科院生物物理所生物大分子国家重点实验室
2000-2009 博士后,University of Illinois,University of Arizona等
工作经历
2009-现在 教授, 博士生导师, 兰州大学萃英特聘教授, 兰州大学生命学院
1996-2000 副教授, 北京师范大学生命学院
1988-1994 助教, 讲师, 兰州大学生物系
教学及指导研究生情况
讲授本科生专题课《植物蛋白组学概论》
讲授研究生课程《植物蛋白组学研究进展》
实验室现有博士研究生4名:郑晟,王立光,武学霞,樊立刚。
实验室现有硕士研究生7名:潘婷,任玲,段育龙,赵雷,万鹏,刘亚芬,袁亚鹏。
发表论文及专著
1. Qiu QS. V-ATPase, ScNhx1p and yeast vacuole fusion. JGG, 2012, 10.1016/j.jgg.2012.02.001
2. Qiu QS. Plant and yeast NHX antiporters: roles in membrane trafficking. J Integr Plant Biol, 2012, 54: 66–72
3. Sasser T, Qiu QS*, Karunakaran S, Padolina M, Reyes A, Flood B, Smith S, Gonzales C, Fratti RA.The yeast lipin 1 orthologue Pah1p regulates vacuole homeostasis and membrane fusion. J Biol Chem, 2012, 287: 2221–2236 (*Co-first author)
4. Qiu QS, Fratti RA.The Na+/H+ exchanger Nhx1p regulates the initiation of Saccharomyces cerevisiae vacuole fusion. J Cell Sci, 2010, 123: 3266-3275
5. Qiu QS, Huber JL, Booker FL, Jain V, Leakey A, Fiscus EL, Yau PM, Ort DR, Huber SC. Increased protein carbonylation in leaves of Arabidopsis and soybean in response to elevated [CO2] and [O3]. Photosyn Res, 2008, 97:155-66
6. Qiu QS, Hardin SC, Brutnell TP, Huber SC. Light and metabolic signals control the selective degradation of SUS in maize leaves during de-etiolation. Plant Physiol, 2007, 144: 468-478
7. Fuglsang AT, Guo Y, Cuin TA, Qiu QS, Song C, Kristiansen KA, Bych K, Schulz A, Shabala S, Schumaker KS, Palmgren MG, Zhu JK. Protein kinase PKS5 inhibits the plasma membrane H+-ATPase by preventing interaction with 14-3-3 protein. Plant Cell, 2007, 19:1617-34
8. Batelli G, Verslues PE, Agius F, Qiu QS, Fujii H, Pan S, Schumaker KS, Grillo S, Zhu JK. SOS2 promotes salt tolerance in part by interacting with the vacuolar H+-ATPase and upregulating its transport activity. Mol Cell Biol 2007, 27:7781-90
9. Qiu QS, Guo Y, Quintero FJ, Pardo JM, Schumaker KS, Zhu JK. Regulation of Vacuolar Na+/H+ Exchange in Arabidopsis thaliana by the Salt-Overly-Sensitive (SOS) Pathway. J Biol Chem, 2004, 279: 207.
10. Guo Y, Qiu QS, Quintero FJ, Pardo JM, Ohta M, Zhang C, Schumaker KS, Zhu JK. Transgenic Evaluation of Activated Mutant Alleles of SOS2 Reveals a Critical Requirement for Its Kinase Activity and C-Terminal Regulatory Domain for Salt Tolerance in Arabidopsis thaliana. Plant Cell, 2004, 16:435.
11. Song CP, Guo Y, Qiu QS, Lambert G, Galbraith DW, Jagendorf A, Zhu JK. A probable Na+(K+)/H+ exchanger on the chloroplast envelope functions in pH homeostasis and chloroplast development in Arabidopsis thaliana. Proc Natl Acad Sci U S A, 2004, 101, 10211.
12. Qiu QS, Vera-Estrella R, Barkla BJ, Zhu JK, Schumaker KS. Na+/H+ exchange activity in the plasma membrane of Arabidopsis thaliana. Plant Physiol, 2003,132 1041.
13. Qiu QS, Guo Y, Dietrich MA, Schumaker KS, Zhu JK. Regulation of SOS1, a plasma membrane Na+/H+ exchanger in Arabidopsis thaliana, by SOS2 and SOS3. Proc Natl Acad Sci U S A, 2002, 99, 8436.
14. Qiu QS, Zhang N. Water stress inhibited PNPP hydrolysis activity of the plasma membrane H+-ATPase from soybean hypocotyls. Australian J. Plant Physiol., 2000,27: 717
15. Qiu QS,Wang ZZ, Zhang N, Cai QG, Jiang RX. Aquaporins at the leaf callus protoplasts from Actinidia deliciosa var deliciosa cv. Hayward. Australian J. Plant Physiol., 2000,27:71
16. Qiu QS. Characterization of PNPP hydrolysis by plasma membrane H+-ATPases from soybean hypocotyls. J. Plant Physiol , 1999,154:628
17. Qiu QS, Su XF. The influence of extracellular side Ca2+ on the activity of the plasma membrane H+-ATPase from wheat roots. Australian J. Plant Physiol. 1998, 25(8):923
18. Qiu QS, Cheng P, Liang HG. Characterization of the NAD(P)H oxidation by purified plasma membrane vesicles using a spin-trapping EPR method. J. Plant Physiol. 1995,146: 445
19. Qiu QS, Liang HG. Lipid peroxidation caused by the redox system of plasma membranes from wheat roots. J. Plant Physiol. 1995, 145: 261
20. Qiu QS, Liang HG, Zheng HJ, Cheng P. Ca2+-calmodulin-stimulated superoxide generation by purified plasma membrane from wheat roots. Plant Science, 1994,101: 99
研究方向
1.植物跨膜离子转运:以拟南芥为模式植物,研究Na+(K+)/H+反向交换体离子转运的生化特性和调节机理及其在离子平衡,pH调节和植物耐盐胁迫方面的生物学功能。
2.生物膜融合:以酵母和拟南芥为模式生物,研究膜微囊转运(vesicle trafficking)和生物膜融合(membrane fusion)的分子机理及其在信号转导和蛋白质分拣过程中的作用。
项目成果
荣誉、获奖
社会工作
2012-现在 《西北植物学报》编委
其它信息
学习经历
1998.09-2001.07:四川大学生命科学学院植物学专业,理学博士
1995.09-1998.07:四川大学生命科学学院植物学专业,理学硕士
1991.09-1995.07:四川大学生物系植物学专业,理学学士
1998.09-2001.07: Ph.D., Botany, College of Life Sciences, Sichuan University
1995.09-1998.07: M.S., Botany, College of Life Sciences, Sichuan University
1991.09-1995.07: B.S., Botany, Department of Biology, Sichuan University
工作经历
2009.10-目前: 兰州大学萃英特聘教授,博士生导师,兰州大学生命科学学院
2001.10-2009.09:博士后,The University of Oklahoma,USA
2009.10-Present: Professor of plant biology, School of Life Sciences, Lanzhou University, China
2001.10-2009.9: Postdoctoral research associate, Department of Microbiology and Plant Biology, University of Oklahoma, USA
教学及指导研究生情况
1、研究生招生(Masters and Ph.D. Programs):
硕士研究生招生 专业:植物学(071001);方向:植物分子生物学、植物分子发育生物学、植物细胞信号转导
博士研究生招生 专业:植物学(071001);方向:植物分子遗传学、植物分子发育生物学、植物生殖生物学
目前指导博士研究生8人,硕士研究生6人。
欢迎报考博士、硕士研究生,合作开展博士后研究工作。
Major for master students: Plant Biology (Plant Molecular Biology, Plant Developmental Biology, Plant Cell Signaling)
Major for Ph.D. students: Plant Biology (Plant Molecular Genetics, Plant Developmental Biology, Plant Reproductive Biology)
2、教学(Teaching):
植物生殖与发育生物学(秋季,本科生)/Plant Reproductive & Developmental Biology (Fall, Undergraduate)
植物生殖生物学(秋季,研究生)/Plant Reproductive Biology (Fall, Graduate)
分子克隆与基因工程(秋季,研究生)/Molecular Cloning & Genetic Engineering (Fall, Graduate)
本科生科研训练(本科生)/Independent Study Courses in Plant Biology (Spring/Fall, Undergraduate)
发表论文及专著
Du J, Gao Y, Zhan Y, Zhang S, Wu Y, Xiao Y, Zou Bo, He K, Gou X, Li G, Lin H, Li J. (2016). Nucleocytoplasmic trafficking is essential for BAK1 and BKK1-mediated cell-death control. Plant Journal, doi: 10.1111/tpj.13125.
Zhang J, Yuan T, Duan X, Wei X, Li J, Russell SD, Gou X. (2016). Cis-regulatory elements determine germline specificity and expression level of an isopentenyltransferase gene in sperm cells of Arabidopsis. Plant Physiology, doi:10.1104/pp.15.01510.
Yue J, Qin Q, Meng S, Jin H, Gou X, Li J, Hou S. (2016). TOPP4 regulates the stability of phytochrome interacting factor 5 during photomorphogenesis in Arabidopsis. Plant Physiology, doi:10.1104/pp.15.01729.
Wu Y, Xun Q, Guo Y, Zhang J, Cheng K, Shi T, He K, Hou S, Gou X, Li J. (2016) Genome-wide expression pattern analyses of the Arabidopsis leucine-rich repeat receptor-like kinases. Molelular Plant, 10.1016/j.molp.2015.12.011.
Shi T, Dimitrov I, Zhang Y, Tax FE, Yi J, Gou X, Li J. (2015). Accelerated rates of protein evolution in barley grain and pistil biased genes might be legacy of domestication. Plant Molecular Biology, 89: 253-261.
Anderson S, Johnson C, Jones D, Conrad L, Gou X, Russell SD, Sundaresan V. (2013). Transcriptomes of isolated rice gametes characterized by deep sequencing: Evidence for distinct sex-dependent chromatin and epigenetic states before fertilization. Plant Journal, 76: 729-741.
Russell SD, Gou X, Wong CE, Wang XK, Yuan T, Wei XP, Bhalla PL, Singh MB. (2012). Genomic profiling of rice sperm cell transcripts reveals conserved and distinct elements in the flowering plant male germ lineage. New Phytologist, 195: 560-573.
Du J, Yin H, Zhang S, Wei Z, Zhao B, Zhang J, Gou X, Lin H, Li J. (2012). Somatice embryogenesis receptor kinases control root development mainly via brassinosteroid-independent actions in Arabidopsis thaliana. Journal of Integrative Plant Biology, 54: 388-399.
Gou X, Li J. (2012). Activation tagging. Methods in Molecular Biology, 876. DOI: 10.1007/978-1-61779-809-2_9.
Gou X, Yin H, He K, Du J, Yi J, Xu S, Lin H, Clouse SD, Li J. (2012). Genetic evidence for an indispensable role of somatic embryogenesis receptor kinases in brassinosteroid signaling. PLoS Genetics, 8: e1002452.
Li J, Du J, He K, Gou X. (2011). Control of cell death by Receptor Kinases in Arabidopsis thaliana. In "Receptor-like Kinases in Plants: From Development to Defense (eds Birgit Kemmerling and Frans Tax)". Signaling and Communication in Plants (ed. Frantisek Baluska, Springer Publisher), Volume 13, pp79-91.
An J, Guo Z, Gou X, Li, J. (2011) TCP1 positively regulates the expression of DWF4 in Arabidopsis thaliana. Plant Signaling & Behavior, 6: 1117-1118.
Ge L, Gou X, Yuan T, Strout GW, Nakashima J, Blancaflor EB, Tian HQ, Russell SD. (2010). Migration of sperm cells during pollen tube elongation in Arabidopsis thaliana: behavior during transport, maturation and upon dissociation of male germ unit associations. Planta, 233:325-332.
Guo Z, Fujioka S, Blancaflor EB, Miao S, Gou X, Li J. (2010). TCP1 controls brassinosteroid biosynthesis by regulating the expression of the key biosynthetic gene DWARF4 in Arabidopsis thaliana. Plant Cell 22, 1161-1173.
Russell SD, Gou X, Wei X, Yuan T. (2010). Male gamete biology in flowering plants. Biochemical Society Transactions 38, 598-603.
Yang H, Gou X, He K, Xi D, Du J, Lin H, Li J. (2010). BAK1 and BKK1 in Arabidopsis thaliana confer reduced susceptibility to turnip crinkle virus. European Journal of Plant Pathology 127, 149-156.
Gou X, He K, Yang H, Yuan T, Clouse SD, Li J. (2010). Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana. BMC Genomics 11, 19.
Gou X, Yuan T, Wei X, Russell SD. (2009). Gene expression in the dimorphic sperm cells of Plumbago zeylanica: Transcript profiling, diversity, and relationship to cell type. Plant Journal 60, 33-47.
He K, Gou X, Powell RA, Yang H, Yuan T, Guo Z, Li J. (2008). Receptor-like protein kinases, BAK1 and BKK1, regulate a light-dependent cell-death control pathway. Plant Signaling & Behavior 3: 813-815.
Li J, Gou X. (2007). Brassinosteroids. In Handbook of plant science (Roberts, K., ed). John Wiley & Sons, Ltd, pp. 395-404.
He K, Gou X, Yuan T, Lin H, Asami T, Yoshida S, Russell SD, Li J. (2007). BAK1 and BKK1 regulate brassinosteroid-dependent growth and brassinosteroid-independent cell-death pathways. Current Biology 17, 1109-1115.
Yuan T, Fujioka S, Takatsuto S, Matsumoto S, Gou X, He K, Russell SD, Li J. (2007). BEN1, a gene encoding a dihydroflavonol 4-reductase (DFR)-like protein, regulates the levels of brassinosteroids in Arabidopsis thaliana. Plant Journal 51, 220-233.
Wei X, Gou X, Yuan T, Russell SD. (2006). A highly efficient in vitro plant regeneration system and Agrobacterium-mediated transformation in Plumbago zeylanica. Plant Cell Rep 25, 513-521.
研究方向
(1)受体激酶介导的细胞信号转导。受体激酶(RLKs)分布在细胞表面,从胞外环境获取信号并传递到细胞内启动下游的基因表达和调控,从而让植物体对各种信号作出正确的反应。在拟南芥中有600个以上的受体激酶,到目前为止只对其中很少一部分基因的功能有所了解。我们克隆了其中绝大部分受体激酶的全长cDNA,并转化野生型拟南芥进行了超表达,目前正致力于解析这些受体激酶的生物学功能。
Functional Analysis of Receptor Kinases
There are more than 600 receptor-like kinases (RLKs) in Arabidopsis that locate on the surface of cells to perceive and transduce chemical signals into cells, regulating downstream gene expression and responding to a variety of biotic or abiotic stimuli. So far, biological functions have been defined for only a handful of RLKs that play crucial roles in many physiological processes in plant. My research is focusing on revealing the functions of these RLKs. Preliminary studies showed that gene members of a couple of RLK subfamilies regulate anther and ovary development, and zygotic embryogenesis, which is under intensive investigation.
(2)植物生殖生物学。被子植物双受精是一个复杂的过程,一个精细胞与卵细胞融合形成合子,发育成胚胎,是下一代植物的雏形;另一个精细胞与中央细胞融合形成胚乳,为胚胎发育提供营养。双受精的成败关系到植物种群的延续,同时也关系到绝大部分农作物的产量与质量。实验室目前的工作主要是利用模式植物拟南芥研究雌雄生殖器官以及性细胞发育调控的分子机理,以及早期胚胎发育调控的信号途径。
Plant Reproductive Biology
Double fertilization is a very complex biological process of angiosperms. After transferred into embryo sac by pollen tube, one sperm cell fuses with the egg cell, forming the zygote that will develop into the embryo, and the other sperm cell fuses with the center cell to generate the endosperm that provides nutrients for embryo development. Successful double fertilization is critical for the survival and development of every species, and is also crucial for the quantity and quality of the production of many crops. Plants have complex regulatory systems to regulate the development of sexual organs to achieve successful double fertilization and embryogenesis. My current research is focusing on those genes involved in anther, ovule and embryo development.
项目成果
实验室得到国家自然科学基金委员会、教育部、科技部和兰州大学的经费支持。
1、主持项目:
国家自然科学基金面上项目《拟南芥富含亮氨酸重复类受体激酶调控合子胚胎发育的分子机理》(No.31070283)
国家自然科学基金面上项目《拟南芥珠被发育的信号网络与调控机理》(No.31270229)
国家自然科学基金面上项目《PzIPT1在拟南芥精细胞中表达的分子机理研究》(No.31471402)
教育部新世纪优秀人才支持计划项目《受体激酶调控花药发育的分子机理》(No. NCET-12-0249)
教育部科学技术项目《受体激酶SERKs调控拟南芥胚胎发育的信号通路》(No.113058A)
2、参加项目:
国家自然科学基金重大研究计划重点项目《一类植物特有的转录因子TCP在油菜素内酯生物合成及信号转导中的调控机理》(No.90917019)
教育部“长江学者和创新团队发展计划”创新团队项目《植物多重抗逆的分子机理》(Nos.IRT0924, IRT_13R25)
科技部重大科学研究计划课题《植物蛋白的修饰的重要过程与调控机理》(No.2011CB9154001)
荣誉、获奖
教育部新世纪优秀人才支持计划(2012)
学习经历
1997.9--2001.7:甘肃农业大学,学士
2001.9--2004.7:甘肃农业大学,硕士
2004.9--2007.7:北京师范大学,博士
2008.5--2011.8:兰州大学,在职博士后
2010.2--2011.8:美国杜克大学,访问学者
工作经历
2007.7--2013.5:兰州大学,副教授
2013.5--至今:兰州大学,教授
教学及指导研究生情况
发表论文及专著
*代表通讯作者,#代表共同第一作者
[1] Yue Niu*, Dong Qian, Baiyun Liu, Jianchao Ma, Dongshi Wan, Xinyu Wang, Wenliang He, Yun Xiang*. ALA6, a P4-type ATPase, Is Involved in Heat Stress Responses in Arabidopsis thaliana. Frontiers in Plant Science, 2017, https://doi.org/10.3389/fpls.2017.01732.
[2] Hui Su*, Hualing Feng, Xiaoting Chao, Xia Ding, Qiong Nan, Chenxi Wen, Huidong Liu, Sinuo Liu, Yun Xiang*, Wenzhe Liu*, Fimbrins 4 and 5 Act Synergistically During Polarized Pollen-tube Growth to Ensure Fertility in Arabidopsis. Plant and Cell Physiology, 2017, https://doi.org/10.1093/pcp/pcx138.
[3] Jingen Zhu#, Qiong Nan#, Tao Qin#, Dong Qian, Tonglin Mao, Shunjie Yuan, Xiaorong Wu, Yue Niu, Qifeng Bai, Lizhe An, Yun Xiang*, Higher-ordered Actin Structures Remodeled by Arabidopsis ACTIN-DEPOLYMERIZING FACTOR5 Are Important for Pollen Germination and Pollen Tube Growth. Molecular Plant, 2017, 10: 1065-1081.
[4] Qiong Nan#, Dong Qian#, Yue Niu, Yongxing He, Shaofei Tong, Zhimin Niu, Jianchao Ma, Yang Yang, Lizhe An, Dongshi Wan*, Yun Xiang*, Plant Actin-depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes Throughout Evolution. Plant Cell, 2017, 29(2): 395-408. (Highlighted paper by Science Editor in “In Brief” )
Jennifer Lockhart, Loose-Knit Family: Tracing the Evolution of Actin-Depolymerizing Factors That Sever or Join the Actin Cytoskeleton. Plant Cell, 2017, 29 (2): 200-201, DOI: https://doi.org/10.1105/tpc.17.00088.
[5] Jiangtao Liu, Yuelong Zhou, Changxin Luo, Yun Xiang, Lizhe An*, De Novo Transcriptome Sequencing of Desert Herbaceous Achnatherum splendens (Achnatherum) Seedlings and Identification of Salt Tolerance Genes. Genes, 2016, 23: 7(4): 12.
[6] Hui Wang, Shengcheng Han, Wei Siao, Chunqing Song, Yun Xiang, Xiaorong Wu, Pengyu Cheng, Hongjuan Li, Ján Jásik, Karol Mi?ieta, Ján Turňa, Boris Voigt, Franti?ek Balu?ka, Jin Liu, Yingdian Wang, Heping Zhao*, Arabidopsis Synaptotagmin 2 Participates in Pollen Germination and Tube Growth and Is Delivered to Plasma Membrane via Conventional Secretion. Molecular Plant, 2015, 8(12):1737-1750.
[7] Dong Qian, Qiong Nan, Yang Yang, Hui Li, Yuelong Zhou, Jingen Zhu, Qifeng Bai, Pan Zhang, Lizhe An, Yun Xiang*, Gelsolin-Like Domain 3 Plays Vital Roles in Regulating the Activities of the Lily Villin/Gelsolin/Fragmin Superfamily. PLoS One, 2015, 10(11): e0143174.
[8] Jingen Zhu, Xiaorong Wu, Shunjie Yuan, Dong Qian, Qiong Nan, Lizhe An, Yun Xiang* (2014) Annexin5 Plays a Vital Role in Arabidopsis Pollen Development via Ca2+-Dependent Membrane Trafficking. PLoS One, 2014, 9(7): e102407.
[9] Jingen Zhu, Shunjie Yuan, Guo Wei, Dong Qian, Xiaorong Wu, Honglei Jia, Mengyuan Gui, Wenzhe Liu, Lizhe An*, Yun Xiang*, Annexin5 is Essential for Pollen Development in Arabidopsis. Molecular Plant, 2014, 7(4): 751-754.
[10] Honglei Jia, Jisheng Li, Jingen Zhu, Tingting Fan, Dong Qian, Yuelong Zhou, Jue Wang, Haiyun Ren, Yun Xiang*, Lizhe An*, Arabidopsis CROLIN1, a Novel Plant Actin-binding Protein, Functions in Cross-linking and Stabilizing Actin Filaments. Journal of Biological Chemisty, 2013, 288: 32277-32288.
[11] Tingting Fan, Huanhuan Zhai, Wenwei Shi, Jue Wang, Honglei Jia, Yun Xiang*, Lizhe An*, Overexpression of Profilin 3 Affects Cell Elongation and F-actin Organization in Arabidopsis thaliana. Plant Cell Reports, 2013, 32(1): 149-160.
[12] Binyun Ma, Dong Qian, Qiong Nan, Chang Tan, Lizhe An*, Yun Xiang*, Arabidopsis V-ATPase B Subunits Are Involved in Actin Cytoskeleton Remodeling via Binding to, Bundling and Stabilizing F-actin. Journal of Biological Chemisty, 2012, 287: 19008-19017.
[13] Jue Wang, Dong Qian, Tingting Fan, Honglei Jia, Lizhe An*, Yun Xiang*, Arabidopsis Actin Capping Protein (AtCP) Subunits Have Different Expression Patterns, and Downregulation of AtCPB Confers Increased Thermotolerance of Arabidopsis after Heat Shock Stress. Plant Science, 2012, 193: 110-119.
[14] Shanjin Huang, Yun Xiang, Haiyun Ren. (2011). Actin-binding Proteins and Actin Dynamics in Plant Cells. In The Plant Cytoskeleton, 2011, pp. 57-80. Springer New York.
[15] Binyun Ma, Yun Xiang, Lizhe An*, Structural Bases of Physiological Functions and Roles of the Vacuolar H+-ATPase. Cellular Signalling, 2011, 23: 1244-1256.
[16] Ting Wang#, Yun Xiang#, Jian Hou, Haiyun Ren*, ABP41 is Involved in the Pollen Tube Development via Fragmenting Actin Filaments. Molecular Plant, 2008, 1(6): 1048-1055.
[17] Yun Xiang, Xi Huang, Ting Wang, Yan Zhang, Qinwen Liu, Patrick J Hussey, Haiyun Ren*, ACTIN BINDING PROTEIN29 from Lilium Pollen Plays an Important Role in Dynamic Actin Remodeling. Plant Cell, 2007, 19(6): 1930-1946.
[18] Haiyun Ren*, Yun Xiang, The Function of Actin-binding Proteins in Pollen Tube Growth. Protoplasma, 2007, 230(3-4): 171-182.
研究方向
微丝骨架(actin cytoskeleton)是遍布于一切真核细胞中的三维网状结构,占植物总蛋白的15-20%,在维持细胞形态、参与细胞运动、胞质分裂和极性建立等重要细胞生理活动中起着决定性的作用。微丝骨架的动态变化是其行使各种生理功能的基础,而该过程则直接受到诸多微丝结合蛋白和不同信号分子的调控。本课题组以模式作物拟南芥为材料,主要开展如下研究工作:
1. 探索植物特有的、功能未知的微丝结合蛋白;
2. 微丝骨架参与植物花粉管极性生长的分子机理;
3. 微丝骨架参与植物响应各种非生物胁迫的分子机理;
4. 植物抗逆信号转导(钙离子)。
项目成果
1. 国家自然科学基金-优秀青年科学基金项目,31722005,植物细胞骨架,2018/01-2020/12,在研,主持
2. 国家自然科学基金-面上项目,31670180,拟南芥微丝解聚因子第三亚家族成员生理生化功能研究,2017/01-2020/12,在研,主持
3. 国家自然科学基金-面上项目,31470283,拟南芥微丝交联蛋白CROLINs调控花粉管生长的分子机理研究,2015/01-2018/12,在研,主持
4. 教育部"新世纪优秀人才支持计划",NCET-13-0264,植物细胞骨架,2014/01-2015/12,已结题,主持
5. 国家自然科学基金-面上项目,31270326,拟南芥液泡氢ATP酶B亚基不同异形体的生理生化功能及作用机理研究,2013/01-2016/12,已结题,主持
6. 甘肃省杰出青年基金,2013GS10064,微丝骨架参与植物响应干旱和高盐胁迫分子机理研究,2013/01-2015/12,已结题,主持
7. 国家自然科学基金-青年科学基金,30800079,拟南芥膜联蛋白annexin5调控花粉管极性生长的分子机制研究,2009/01-2011/12,已结题,主持
荣誉、获奖
1. 国家优秀青年基金(2017)
2. 教育部"新世纪优秀人才支持计划"(2013)
3. 甘肃省杰出青年基金(2013)